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Indian J Pediatr ; 2003 Nov; 70(11): 923-4
Article in English | IMSEAR | ID: sea-80994

ABSTRACT

Losartan is a specific angiotensin II receptor antagonist. Although the teratogenic effects of angiotensin converting enzyme (ACE) inhibitors are well documented there are limited reports of losartan induced fetal toxicity. The authors report a case of incomplete ossification of skull bones, transient oliguria and feed intolerance in a newborn following in-utero exposure to losartan.


Subject(s)
Abnormalities, Drug-Induced , Antihypertensive Agents/poisoning , Female , Fetal Death/chemically induced , Heart Defects, Congenital/drug therapy , Humans , Losartan/poisoning , Pregnancy , Pregnancy Complications, Cardiovascular/drug therapy
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